Carnosine, Milk Thistle and Vitamin E Blend
Carnosine, Milk Thistle and Vitamin E in Vivo Study
Clinical tests demonstrate topical application of carnosine (an amino acid) and vitamin E, two
powerful antioxidants, plus milk thistle extract, a detoxifier, resulted in increased firmness
and hydration, and advanced anti-wrinkle and anti-glycation activity on the skin.
Glycation happens when sugar molecules bind to collagen and elastin proteins in the skin to
form damaging free radicals (not unlike the free radicals caused by too much sun). Free
radicals are a primary cause of aging. They lead to inflammation, which in turn breaks down
the skin's connective tissue, resulting in wrinkles, yellowing of the skin, loss of elasticity due
to a hardening of collagen and elastin fibers in the dermis, and other visible signs of aging.
Studies conducted over 28 days show a synergistic blend of these three ingredients in a
liposome delivery system helps stop glycation by preventing glucose/collagen bonds from
forming and breaking down free radicals already present in the skin.
Rejuvenating Properties of Carnosine, Milk Thistle & Vitamin E
This study involved 20 women
ages 38 to 65. A test cream
containing a liposome
preparation of 2% carnosine,
milk thistle and vitamin E was
applied to the inner forearm of
the subjects twice a day for 28
Biomechanical properties of the
skin were then evaluated by
determining the skin's firmness,
hydration and smoothness.
Results showed this preparation
improved all parameters in all
subjects after 28 days of
treatment when compared to
A test cream containing a liposome
preparation of 2% carnosine, milk
thistle and vitamin E was applied
twice daily for 28 days to the
crow's feet and foreheads of 20
women ages 38 to 65.
Wrinkle depth was evaluated after
14 days of treatment and again
after 28 days. Results showed that
at the 14 day mark, the depth of
wrinkles was somewhat
diminished. After 28 days of
treatment, depth of wrinkles had
been reduced by 27% in the
crow's feet area, and by 24% on
*Permission to use study and photographs given to Aubrey Organics, Inc.
May not be used or distributed without written consent of Mibelle ©.